摘要 |
The present invention relates to polymorphic forms of 7-(4-Bromo-2-fluoro-phenylamino)-6-methyl-5-oxo-1,3,5-tetrahydro-indolizine-8-carboxylic acid (2-hydroxy-ethoxy)-amide and a hydrate thereof which are useful in the treatment of a disease, disorder or syndrome associated with MEK inhibition, such as cancer, in mammals. The invention also relates to compositions thereof and to methods of using such compositions in the treatment of cancer in mammals, especially humans. |
申请人 |
NOVARTIS AG;WAYKOLE, LILADHAR, MURLIDHAR;KARPINSKI, PIOTR, H.;XUE, SONG;BELTZ, KAREN;SEILER, FRANK HANS |
发明人 |
WAYKOLE, LILADHAR, MURLIDHAR;KARPINSKI, PIOTR, H.;XUE, SONG;BELTZ, KAREN;SEILER, FRANK HANS |