Disclosed is an antibody capable of binding to DLL3 protein. Preferably, the antibody can recognize an amino acid region lying between the 216th amino acid residue and the 492nd amino acid residue in human DLL3 that comprises the amino acid sequence represented by SEQ ID NO:1. Also disclosed are: a pharmaceutical composition, such as an anti-cancer agent, which contains the antibody as an active ingredient; a method for diagnosing cancer using the antibody; and a diagnostic agent for cancer, which comprises the antibody.
申请公布号
WO2011093097(A1)
申请公布日期
2011.08.04
申请号
WO2011JP00485
申请日期
2011.01.28
申请人
FORERUNNER PHARMA RESEARCH CO., LTD.;THE UNIVERSITY OF TOKYO;YOSHIDA, KENJI;ABURATANI, HIROYUKI;ISHIKAWA, SHUMPEI