| 发明名称 |
SUBSTITUTED ISOQUINOLINES AND ISOQUINOLINONES AS RHO KINASE INHIBITORS |
| 摘要 |
The invention relates to substituted isoquinoline and isoquinolinones of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
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| 申请公布号 |
US2011190341(A1) |
申请公布日期 |
2011.08.04 |
| 申请号 |
US200913000754 |
申请日期 |
2009.06.19 |
| 申请人 |
SANOFI-AVENTIS |
发明人 |
PLETTENBURG OLIVER;LORENZ KATRIN;WESTON JOHN;LOEHN MATTHIAS;KLEEMANN HEINZ-WERNER;DUCLOS OLIVIER;JEANNOT FREDERIC |
| 分类号 |
A61K31/472;A61P9/10;A61P9/12;A61P11/00;A61P13/12;A61P25/00;A61P25/28;A61P35/00;C07D217/24 |
主分类号 |
A61K31/472 |
| 代理机构 |
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