发明名称 |
Compositions and Methods for Treating Collagen-Mediated Diseases |
摘要 |
A drug product comprising a combination of highly purified collagenase I and collagenase II from Colostridium histolyticum is disclosed. The drug product includes collagenase I and collagenase II in a ratio of about 1 to 1, with a purity of greater than at least 95%. The invention further disclosed improved fermentation and purification processes for preparing the said drug product. |
申请公布号 |
US2011189153(A1) |
申请公布日期 |
2011.08.04 |
申请号 |
US201113084716 |
申请日期 |
2011.04.12 |
申请人 |
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发明人 |
SABATINO GREGORY L.;DEL TITO BENJAMIN J.;BASSETT PHILLIP J.;THARIA HAZEL A.;HITCHCOCK ANTONY G. |
分类号 |
A61K38/48;A61P43/00;C12N9/52 |
主分类号 |
A61K38/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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