发明名称 |
METHODS AND COMPOSITIONS FOR INHIBITING RHO-MEDIATED DISEASES AND CONDITIONS |
摘要 |
The invention provides methods, compositions, and kits for the inhibition of members of the Rho GTPase family. Specifically, the invention provides methods, compositions and kits for the inhibition of RhoA and/or RhoC transcriptional signalling. The invention finds use in treatment of Rho-mediated disease states (e.g., tumor metastasis, inflammation, inflammatory disease), Rho-mediated biological conditions, and in cell signaling research. |
申请公布号 |
WO2011035143(A3) |
申请公布日期 |
2011.08.04 |
申请号 |
WO2010US49312 |
申请日期 |
2010.09.17 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN;NEUBIG, RICHARD;EVELYN, CHRIS;RYU, JENNY;LARSEN, SCOTT;BELL, JESSICA |
发明人 |
NEUBIG, RICHARD;EVELYN, CHRIS;RYU, JENNY;LARSEN, SCOTT;BELL, JESSICA |
分类号 |
A61K31/455;A61K31/40;A61K31/4192;A61K31/421;A61K31/551;A61P29/00;A61P35/00 |
主分类号 |
A61K31/455 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|