| 发明名称 |
ANTIBODIES TO VLA-1 |
| 摘要 |
Antibodies that specifically bind to VLA-1 integrin and methods of using these antibodies to treat immunological disorders in a subject. Also included are crystal structures of complexes formed by VLA-1 antibodies and their ligands, and VLA-1 antagonists and agonists identified by using the structure coordinates of these structures.
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| 申请公布号 |
US2011189177(A1) |
申请公布日期 |
2011.08.04 |
| 申请号 |
US201113017919 |
申请日期 |
2011.01.31 |
| 申请人 |
BIOGEN IDEC MA INC. |
发明人 |
KARPUSAS MICHAEL;LYNE PAUL D.;SALDANHA JOSE WILLIAM;GARBER ELLEN A. |
| 分类号 |
A61K39/395;G01N33/50;A61K49/16;A61P1/00;A61P17/00;A61P17/06;A61P19/04;A61P29/00;A61P37/00;A61P37/06;C07H21/04;C07K16/18;C07K16/24;C07K16/28;C07K16/46;C12N;C12N1/00;C12N5/10;C12N5/12;C12N5/20;C12N5/22;C12N9/00;C12N15/07;C12N15/09;C12N15/11;C12N15/13;G01N33/15;G01N33/53;G01N33/543;G01N33/567;G01N33/577;G06F17/00;G06F17/30;G06F19/00;H04N9/64;H04N13/02;H04N15/00 |
主分类号 |
A61K39/395 |
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