<p>Provided are methods for detecting circulating tumor cells (CTCs) in a subject. The methods may include detecting the expression of at least one epithelial mesenchymal transition (EMT) biomarker. Further provided are kits for detecting CTCs. The kits may include antibodies to at least one EMT biomarker. Further provided are methods of predicting the responsiveness of a subject to a cancer drug, methods of targeting delivery of a cancer drug in a subject, methods of providing a cancer prognosis to a subject, and methods for following the progress of cancer in a subject.</p>
申请公布号
WO2011093927(A1)
申请公布日期
2011.08.04
申请号
WO2010US50223
申请日期
2010.09.24
申请人
DUKE UNIVERSITY;GARCIA-BLANCO, MARIANO, A.;ARMSTRONG, ANDREW, J.;GEORGE, DANIEL, J.;OLTEAN, SEBASTIAN
发明人
GARCIA-BLANCO, MARIANO, A.;ARMSTRONG, ANDREW, J.;GEORGE, DANIEL, J.;OLTEAN, SEBASTIAN