| 发明名称 |
PRODRUGS OF OPIOIDS AND USES THEREOF |
| 摘要 |
The present invention concerns prodrugs of opioid analgesics and pharmaceutical compositions containing such prodrugs. Methods for providing more consistent pain relief by increasing the bioavailability of the opioid analgesic with the aforementioned prodrugs are provided. The invention also provides for decreasing the adverse GI side effects of opioid analgesics.
|
| 申请公布号 |
US2011190267(A1) |
申请公布日期 |
2011.08.04 |
| 申请号 |
US20100978210 |
申请日期 |
2010.12.23 |
| 申请人 |
SHIRE PHARMACEUTICALS, INC. |
发明人 |
FRANKLIN RICHARD;SWIFT KARL;GOLDING BERNARD T.;TYSON ROBERT G. |
| 分类号 |
A61K31/55;A61K31/27;A61K31/439;A61K31/451;A61P25/04;C07C271/58;C07D211/34;C07D221/28;C07D223/04;C07D401/12;C07D489/02 |
主分类号 |
A61K31/55 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
