METHODS OF DIAGNOSING TAU-ASSOCIATED NEURODEGENERATIVE DISEASES
摘要
<p>This invention provides methods and kits for the detection of tau- associated neurodegenerative diseases, such as Alzheimer's disease, prior to the onset of clinical symptoms. The method generally involves determining the amount of one or more tau protein isoforms in a biological sample relative to a suitable control, where an altered amount of the tau isoform(s) relative to the control identifies the presence of a tau- associated neurodegenerative disease. Such methods can also be applied more generally for the detection of tau abnormalities in any biological sample.</p>
申请公布号
WO2011094645(A1)
申请公布日期
2011.08.04
申请号
WO2011US23065
申请日期
2011.01.28
申请人
UNIVERSITY OF MASSACHUSETTS LOWELL;HALL, GARTH, F.;KIM, WONHEE;LEE, SANGMOOK