发明名称 NUCLEOSIDE TRIPHOSPHATE DERIVATIVE, NUCLEIC ACID PROBE, MULTILABELED NUCLEIC ACID PROBE, METHOD FOR PRODUCTION OF MULTILABELED NUCLEIC ACID PROBE, AND METHOD FOR DETECTION OF TARGET NUCLEIC ACID
摘要 A novel nucleoside triphosphate derivative, a nucleic acid probe, and a multilabeled nucleic acid probe that can detect a target nucleic acid conveniently and with high sensitivity, as well as a method for producing the multilabeled nucleic acid probe, and a method for detecting a target nucleic acid using the multilabeled nucleic acid probe or the nucleic acid probe. A target nucleic acid can be detected conveniently and with high sensitivity by using a transglutaminase (TGase), and by using a multilabeled nucleic acid probe in which a plurality of labeling portions have been introduced in advance by covalent binding, or by introducing a plurality of labeling portions by covalent binding into a nucleic acid probe that has been hybridized with the target nucleic acid.
申请公布号 US2011189671(A1) 申请公布日期 2011.08.04
申请号 US200913003380 申请日期 2009.07.22
申请人 KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION;THE UNIVERSITY OF TOKUSHIMA;ALOKA CO., LTD. 发明人 KAMIYA NORIHO;NOJI SUMIHARE;HIRAISHI YOSHIYUKI
分类号 C12Q1/68;C07H19/10;C07H19/20;C07H21/00;C12N9/96;C12P21/00 主分类号 C12Q1/68
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