发明名称 |
NUCLEOSIDE TRIPHOSPHATE DERIVATIVE, NUCLEIC ACID PROBE, MULTILABELED NUCLEIC ACID PROBE, METHOD FOR PRODUCTION OF MULTILABELED NUCLEIC ACID PROBE, AND METHOD FOR DETECTION OF TARGET NUCLEIC ACID |
摘要 |
A novel nucleoside triphosphate derivative, a nucleic acid probe, and a multilabeled nucleic acid probe that can detect a target nucleic acid conveniently and with high sensitivity, as well as a method for producing the multilabeled nucleic acid probe, and a method for detecting a target nucleic acid using the multilabeled nucleic acid probe or the nucleic acid probe. A target nucleic acid can be detected conveniently and with high sensitivity by using a transglutaminase (TGase), and by using a multilabeled nucleic acid probe in which a plurality of labeling portions have been introduced in advance by covalent binding, or by introducing a plurality of labeling portions by covalent binding into a nucleic acid probe that has been hybridized with the target nucleic acid. |
申请公布号 |
US2011189671(A1) |
申请公布日期 |
2011.08.04 |
申请号 |
US200913003380 |
申请日期 |
2009.07.22 |
申请人 |
KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION;THE UNIVERSITY OF TOKUSHIMA;ALOKA CO., LTD. |
发明人 |
KAMIYA NORIHO;NOJI SUMIHARE;HIRAISHI YOSHIYUKI |
分类号 |
C12Q1/68;C07H19/10;C07H19/20;C07H21/00;C12N9/96;C12P21/00 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|