发明名称 TRANSITION METAL COMPLEXES OF BIS[THIOHYDRAZIDE AMIDE] COMPOUNDS
摘要 <p>The present invention is directed to a compound comprising a bis[thiohydrazide amide] or a deprotonated form thereof, complexed to a transition metal cation, wherein the bis[thiohydrazide amide] is represented by Structural Formula (I), or a prodrug, isomer, ester, salt, hydrate, solvate, polymorph or a deprotonated form thereof. In one embodiment, the compound is represented by Structural Formula (II), or a prodrug, isomer, ester, salt, hydrate, solvate or polymorph thereof. The present invention also provides a pharmaceutical composition comprising the compound of the invention and method of use thereof.</p>
申请公布号 EP2349991(A1) 申请公布日期 2011.08.03
申请号 EP20090822624 申请日期 2009.10.21
申请人 SYNTA PHARMACEUTICALS CORP. 发明人 NAGAI, MASAZUMI;SHEN, JIANHUA
分类号 C07C327/00;A61K31/555;A61P35/00;C07C327/56;C07D213/83;C07D231/14;C07D307/68 主分类号 C07C327/00
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