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发明名称
MMP ACTIVATED VASCULAR DISRUPTING AGENTS
摘要
The present invention relates to prodrugs of vascular disrupting agents comprising a vascular disrupting agent (VDA) associated with a MMP proteolytic cleavage site and to the use of such prodrugs in the targeted treatment of cancer.
申请公布号
EP2349344(A1)
申请公布日期
2011.08.03
申请号
EP20090760548
申请日期
2009.10.20
申请人
UNIVERSITY OF BRADFORD
发明人
FALCONER, ROBERT, ANDREW;GILL, JASON;ATKINSON, JENNIFER;LOADMAN, PAUL;BIBBY, MICHAEL;PATTERSON, LAURENCE
分类号
A61K47/48;A61P35/00;C07K7/06
主分类号
A61K47/48
代理机构
代理人
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