发明名称 USE OF MUTATED VEGF FOR ANTIANGIOGENIC THERAPY
摘要 The invention relates to the application of oligonucleotide and polypeptide sequences of molecules belonging to the vascular permeability factor (VPF) family, their receptors and co-receptors and to their modifications in active immunotherapy against pathological entities whose course is associated with an increase in vasculature. Said procedures can be used, inter alia, in monotherapy or combined therapy for the treatment of cancer and its metastasis, acute and chronic inflammatory processes, infectious diseases, autoimmune diseases, diabetic and infant retinopathy, rejection of transplanted organs, macular degeneration, neovascular glaucoma, hemangioma and angiofibroma.
申请公布号 PT1502599(E) 申请公布日期 2011.08.03
申请号 PT20030711811T 申请日期 2003.04.11
申请人 CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CIGB) 发明人 MONICA BEQUET ROMERO;BORIS ERNESTO ACEVEDO CASTRO;JORGE VICTOR GAVILONDO COWLEY;LUIS ENRIQUE CALLE FERNANDEZ MOLINA;OMAR LOPEZ OCEJO;RICARDO DE LA CARIDAD SILVA RODRIGUEZ;ALEXIS MUSACHIO LASA;GALBAN RODRIGUEZ, ERNESTO;DANIA MARCIA VAZQUEZ BLOMQUIST
分类号 A61K38/19;A61K38/18;A61K39/00;A61K48/00;A61P35/00;A61P43/00;C07K14/515;C07K14/52;C07K14/71;C07K14/715;C12N15/12 主分类号 A61K38/19
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