发明名称 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
摘要 A compound for use in treating polycystic kidney disease is represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating polycystic kidney disease in a subject in need thereof comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. Methods of treating in polycystic kidney disease in a subject in need thereof respectively comprise administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.
申请公布号 EP2349255(A1) 申请公布日期 2011.08.03
申请号 EP20090741487 申请日期 2009.10.02
申请人 GENZYME CORPORATION 发明人 SIEGEL, CRAIG;BASTOS, CECILIA, M.;HARRIS, DAVID, J.;DIOS, ANGELES;LEE, EDWARD;SILVA, RICHARD;CUFF, LISA, M.;LEVINE, MIKAELA;CELATKA, CASSANDRA, A.;JOZEFIAK, THOMAS, H.;VINICK, FREDERIC;XIANG, YIBIN;KANE, JOHN;LIAO, JUNKAI
分类号 A61K31/4025;C07C271/12;C07D207/10;C07D295/04;C07D295/10;C07D319/08;C07D405/06;C07D405/14;C07D407/14;C07D409/06;C07D409/12;C07D409/14;C07D413/06;C07D413/14;C07D417/14 主分类号 A61K31/4025
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