发明名称 |
NOVEL TETRAHYDROQUINOLINES AS AROMATASE INHIBITORS |
摘要 |
<p>The invention relates to synthesis and biological screening of novel tetrahydroquinolines of formula (I), their derivatives, their stereoisomers, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them for aromatase inhibition: (I). The present invention also relates to a process for the preparation of the novel tetrahydroquinolines, their derivatives, their stereoisomers, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them. These compounds are useful in for aromatase inhibition, particularly in the treatment and/or prevention of cancer, particularly breast cancer, more particularly hormone dependent breast cancer.</p> |
申请公布号 |
EP2291355(A4) |
申请公布日期 |
2011.08.03 |
申请号 |
EP20090701340 |
申请日期 |
2009.01.02 |
申请人 |
PANJAB UNIVERSITY;KAKATIYA UNIVERSITY |
发明人 |
AKKINEPALLY, RAGHURAM, RAO;JAVALI, NARASHIMA, MURTHY |
分类号 |
C07D215/00;A61K31/4725;A61P35/00;C07D215/02;C07D215/12;C07D215/233 |
主分类号 |
C07D215/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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