发明名称 PROMOTER FOR REGENERATION OF TENDON-BONE JUNCTION TISSUE OR LIGAMENT-BONE JUNCTION TISSUE
摘要 An object of the present invention is to provide a drug for promoting the regeneration of tendon-bone junction tissue or ligament-bone junction tissue. The present invention relates to a promoter for regeneration of tendon-bone junction tissue or ligament-bone junction tissue including the following (1) or (2) as an active ingredient: (1) the following (1-a), (1-b), or (1-c) (1-a) HGF protein, (1-b) a partial peptide of HGF protein, the peptide having an effect of promoting regeneration of tendon-bone junction tissue or ligament-bone junction tissue, (1-c) a salt of (1-a) or (1-b); (2) DNA including the following (2-a), (2-b), or (2-c), (2-a) DNA encoding HGF protein, (2-b) DNA encoding a partial peptide of HGF protein, the peptide having an effect of promoting regeneration of tendon-bone junction tissue or ligament-bone junction tissue, (2-c) DNA encoding a protein or a peptide, the protein or the peptide having an effect of promoting regeneration of tendon-bone junction tissue or ligament-bone junction tissue, and the DNA hybridizing with DNA comprising a base sequence complementary to (2-a) or (2-b) under a stringent condition.
申请公布号 EP2351574(A1) 申请公布日期 2011.08.03
申请号 EP20090819250 申请日期 2009.10.08
申请人 KRINGLE PHARMA, INC. 发明人 TOMITA, KATSURO;TSUCHIYA, HIROYUKI;KITAOKA, KATSUHIKO;NAKASE, JUNSUKE;HANADA, KEIGO;MATSUMOTO, KUNIO
分类号 A61K38/18;A61K48/00;A61P19/04;C07K14/475 主分类号 A61K38/18
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