发明名称 |
STATISTICAL COMBINING OF CELL EXPRESSION PROFILES |
摘要 |
A method for fluorophore bias removal in microarray experiments in which the fluorophores used in microarray experiment pairs are reversed. Further, a method for calculating the individual errors associated with each measurement made in nominally repeated microarray experiments. This error measurement is optionally coupled with rank based methods in order to determine a probability that a cellular constituent is up or down regulated in response to a perturbation. Finally, a method for determining the confidence in the weighted average of the expression level of a cellular constituent in nominally repeated microarray experiments. |
申请公布号 |
CA2356696(C) |
申请公布日期 |
2011.08.02 |
申请号 |
CA19992356696 |
申请日期 |
1999.12.27 |
申请人 |
ROSETTA INPHARMATICS, INC. |
发明人 |
STOUGHTON, ROLAND;DAI, HONGYUE |
分类号 |
C12Q1/68;G01N33/53;C12N15/09;G01N33/48;G01N33/566;G01N33/58;G01N37/00;G06F17/18;G06F19/20 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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