发明名称 |
Mutant 6-phosphogluconate dehydrogenase |
摘要 |
The present invention relates to a polypeptide having a modified amino acid sequence of 6-phosphogluconate dehydrogenase (hereinafter abbreviated as GND) derived from a microorganism belonging to the genus Corynebacterium, said modification being substitution of the amino acid residue(s) at the position(s) corresponding to the 158th and/or the 361st amino acid(s) of the amino acid sequence shown in SEQ ID NO: 1, and having GND activity; DNA encoding the polypeptide; a recombinant DNA comprising the DNA; a transformant carrying the recombinant DNA; a microorganism carrying the DNA on the chromosome; and a process for producing a useful substance which comprises culturing the transformant or the microorganism in a medium.
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申请公布号 |
US7989191(B2) |
申请公布日期 |
2011.08.02 |
申请号 |
US20090430592 |
申请日期 |
2009.04.27 |
申请人 |
KYOWA HAKKO BIO CO., LTD. |
发明人 |
IKEDA MASATO;OHNISHI JUNKO;MITSUHASHI SATOSHI;OCHIAI KEIKO |
分类号 |
C12N9/04;C07H21/04;C12N1/20;C12N1/21;C12N15/00;C12N15/53;C12P13/04;C12P13/06;C12P13/08;C12P13/10;C12P13/22;C12P21/04;C12Q1/00;C12Q1/68 |
主分类号 |
C12N9/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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