发明名称 DOSAGE OF OLIGONUCLEOTIDES SUITABLE FOR THE TREATMENT OF TUMORS
摘要 This invention is related to the use of an antisense oligonucleotide, comprising 8 to 30 nucleotide building blocks, which hybridizes with mRNA of TGF-beta 1, -2 and/or -3, VEGF, interleukin 10, c-jun, c-fos, MIA, and/or prostaglandin E2 for the preparation of a pharmaceutical composition for preventing and/or treating a tumor, wherein the antisense oligonucleotide is suitable to be administered intravenously in an amount of 400 to 800 mg/m2/treatment cycle.
申请公布号 KR20110086850(A) 申请公布日期 2011.08.01
申请号 KR20117013540 申请日期 2009.11.13
申请人 ANTISENSE PHARMA GMBH 发明人 SCHLINGENSIEPEN KARL HERMANN;HEINRICHS HUBERT;SCHMAUS SUSANNE
分类号 A61K31/7088;A61K38/18;A61P35/00 主分类号 A61K31/7088
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