| 发明名称 |
IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS |
| 摘要 |
<p>This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo.</p> |
| 申请公布号 |
IL196762(D0) |
申请公布日期 |
2011.07.31 |
| 申请号 |
IL20090196762 |
申请日期 |
2009.01.28 |
| 申请人 |
THE SCRIPPS RESEARCH INSTITUTE;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
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| 分类号 |
C12N15/09;A61K38/00;A61K38/22;A61P7/00;C07K14/00;C07K14/47;C07K14/505;C12N;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/00;C12N15/67;C12P13/00;C12P13/04;C12P13/22;C12P19/26;C12P21/02;C12Q1/02;C12Q1/06 |
主分类号 |
C12N15/09 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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