发明名称 |
PROCESS FOR PREPARATION OF ISOTONIC AQUEOUS INJECTION OF ROPIVACAINE |
摘要 |
<p>The preparation of an injectable solution of ropivacaine by dissolving ropivacaine base in aqueous acidic solution having a molar ratio of acid to ropivacaine base greater than 1:1 eliminates the need for a hydrochloride or hydrochloride monohydrate intermediate in the manufacture of the injectable. The osmolality can be adjusted as needed. The excess acid is neutralized with a base.</p> |
申请公布号 |
SI1883392(T1) |
申请公布日期 |
2011.07.29 |
申请号 |
SI20060030959T |
申请日期 |
2006.05.22 |
申请人 |
NAVINTA, LLC. |
发明人 |
JOBDEVAIRAKKAM CHRISTOPHER N.;RANGISETTY JAGADEESH B. |
分类号 |
A61K9/10 |
主分类号 |
A61K9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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