| 发明名称 |
HUMANIZATION OF RABBIT ANTIBODIES USING A UNIVERSAL ANTIBODY FRAMEWORK. |
| 摘要 |
<p>The present invention relates to an universal antibody acceptor framework and to methods for grafting non-human antibodies, e.g., rabbit antibodies, using a universal antibody acceptor framework. Antibodies generated by the methods of the invention are useful in a variety of diagnostic and therapeutic applications.</p> |
| 申请公布号 |
MX2011000052(A) |
申请公布日期 |
2011.07.29 |
| 申请号 |
MX20110000052 |
申请日期 |
2009.06.25 |
| 申请人 |
ESBATECH, AN ALCON BIOMEDICAL RESEARCH UNIT LLC |
发明人 |
DAVID URECH;LEONARDO BORRAS |
| 分类号 |
C07K16/24;A61K39/395;C07K16/22;C12N15/13 |
主分类号 |
C07K16/24 |
| 代理机构 |
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