发明名称 |
OSTEOBLAST COMPOSITION OF SEMI-SOLIDIFIED MIXED FIBRIN FOR BONE FRACTURE AGGLUTINATION AND ITS MANUFACTURING METHOD |
摘要 |
<p>A method for producing the fibrin contained semi-solid osteoblast composition has developed for treating the bone fracture. The method is comprised of: isolating osteoblasts from a bone tissue and culturing/proliferating the isolated osteoblasts in Dulbecco's Modified Eagle's Medium (DMEM) or Minimum Essential Medium, Alpha Modification (alpha-MEM) to prepare an osteoblast suspension. Then, mixing the resulting osteoblast suspension with a coagulation factor to prepare an osteoblast therapeutic agent. Accordingly, the fibrin contained semi-solid osteoblast composition of the present invention has capability to achieve the bone grafting for performing bone union without the clinical graft rejection. It is possible to uniformly distribute the fibrin mixed semi-solid osteoblast composition into the affected area of the bone fracture via injection. Therefore, the fibrin contained semi-solid osteoblast composition is effectively and rapidly cure the bone fracture via constant injection of into the affected area.</p> |
申请公布号 |
SI1890713(T1) |
申请公布日期 |
2011.07.29 |
申请号 |
SI20050031313T |
申请日期 |
2005.08.03 |
申请人 |
SEWON CELLONTECH CO., LTD. |
发明人 |
PARK HYUN-SHIN;JANG JAE-DEOG;CHANG CHEONG-HO;JUNG SOO-JIN;LEE SAE-BOM;KO CHANG-KWON |
分类号 |
A61K35/32 |
主分类号 |
A61K35/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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