发明名称 AMIDE SUBSTITUTED INDAZOLES AS POLY(ADP-RIBOSE)POLYMERASE (PARP) INHIBITORS
摘要 <p>The present invention relates to compounds of formula I: and pharmaceutically acceptable salts, stereoisomers or tautomers thereof which are inhibitors of poly (ADP-ribose) polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes, neurodegenerative diseases, retroviral infection, retinal damage or skin senescence and UV-induced skin damage, and as chemo- and/or radiosensitizers for cancer treatment.</p>
申请公布号 SI2109608(T1) 申请公布日期 2011.07.29
申请号 SI20080030240T 申请日期 2008.01.08
申请人 ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.R.L. 发明人 JONES PHILIP;ONTORIA ONTORIA JESUS MARIA;SCARPELLI RITA;SCHULTZ-FADEMRECHT CARSTEN
分类号 A61K31/4427 主分类号 A61K31/4427
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