| 发明名称 |
ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES |
| 摘要 |
<p>The invention relates to compounds of the general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNPs) and/or nucleoside hydrolases (NHs). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.</p> |
| 申请公布号 |
SI2057165(T1) |
申请公布日期 |
2011.07.29 |
| 申请号 |
SI20070030602T |
申请日期 |
2007.09.07 |
| 申请人 |
INDUSTRIAL RESEARCH LIMITED GRACEFIELD RESEARCH CENTRE;ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY |
发明人 |
CLINCH KEITH;EVANS GARY BRIAN;FURNEAUX RICHARD HUBERT;KELLY PETER MICHAEL;SCHRAMM VERN L.;TYLER PETER CHARLES;WOOLHOUSE ANTHONY DAVID;GULAB SHIVALI ASHWIN |
| 分类号 |
A61K31/519 |
主分类号 |
A61K31/519 |
| 代理机构 |
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