| 发明名称 |
MODULATION OF BCL11A FOR TREATMENT OF HEMOGLOBINOPATHIES |
| 摘要 |
The invention relates to methods and uses of modulating fetal hemoglobin expression (HbF) in a hematopoietic progenitor cells via inhibitors of BCL11A expression or activity, such as RNAi and antibodies.
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| 申请公布号 |
US2011182867(A1) |
申请公布日期 |
2011.07.28 |
| 申请号 |
US200913063524 |
申请日期 |
2009.09.14 |
| 申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION;PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
ORKIN STUART H.;SANKARAN VIJAY G. |
| 分类号 |
A61K35/12;A61K31/7088;A61P7/00;A61P7/06;C12N5/078;C12N15/113;C12Q1/02;C12Q1/68;G01N33/53 |
主分类号 |
A61K35/12 |
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