PHARMACEUTICAL FORMULATIONS OF LORATADINE FOR ENCAPSULATION AND COMBINATIONS THEREOF
摘要
<p>This invention relates to a loratadine formulation suitable for encapsulation into a soft gel capsule or suitable dosage unit with improved functionality providing enhanced in vitro dissolution and bioavailability of loratadine. The invention also provides a formulation with improved functionality as a highly concentrated solution within a given fill volume in order to manufacture as small a capsule as possible to facilitate consumer acceptance and acceptable manufacturing costs. The invention also relates to a formulation of optimal stability suitable for supporting a fill composition compatible with the soft gel capsule dosage unit.</p>
申请公布号
WO2011088550(A1)
申请公布日期
2011.07.28
申请号
WO2011CA00052
申请日期
2011.01.18
申请人
ACCUCAPS INDUSTRIES LIMITED;OKUTAN, BETH;DRAPER, PETER;DRAPER, JAMES