摘要 |
<p>Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin- modulating compound in combination with another therapeutic agent.</p> |
申请人 |
SIRTRIS PHARMACEUTICALS, INC. |
发明人 |
VU, CHI, B.;MCPHERSON, LAUREN;NG, PUI, YEE;BLUM, CHARLES |