发明名称 |
METHODS FOR INTRACELLULAR DELIVERY OF NUCLEIC ACIDS |
摘要 |
<p>The present invention concerns a method for intracellular delivery of isolated naked nucleic acids into isolated biological tissue or organ, said method comprising at least the steps of: a/ contacting said tissue or organ with an efficient amount of at least one active corticosteroid, and contacting said animal cells treated in step a/ with an efficient amount of isolated naked nucleic acids, said step a/ being carried out for a period of time ranging from at least five minutes to at most two hours and being immediately followed by step b/.</p> |
申请公布号 |
CA2786766(A1) |
申请公布日期 |
2011.07.28 |
申请号 |
CA20112786766 |
申请日期 |
2011.01.14 |
申请人 |
UNIVERSITE PARIS DESCARTES |
发明人 |
BEHAR-COHEN, FRANCINE;TOUCHARD, ELODIE |
分类号 |
C12N15/87;A61K48/00;C07J43/00;C07K14/72 |
主分类号 |
C12N15/87 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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