The present invention is directed to a dried seamless capsule comprising an alginate shell membrane encapsulating fill material, wherein: (i) said alginate shell membrane comprises a polyvalent metal ion alginate having: (a) an average M content of from 50%-62% by weight based on the weight of the M and G content, and (b) a viscosity of 35 to 80 cps when measured as a monovalent metal ion alginate in a 3.5% water solution at 20 ?C using a Brookf?eld LV viscometer at 60 rpm and spindle #1; (ii) said alginate shell membrane encapsulates an oil present in an amount of at least 50% by weight of said fill material; (iii) said dried seamless capsule has a disintegration time of less than 12 minutes in an intestinal buffer after pretreatment for 20 minutes in a solution of 0.1 M NaCl and HCl, pH of 3, at 37 ?C; and (iv) said dried seamless capsule has a dry break force strength of at least 7kg. The present invention is also directed to methods of making and using such dried seamless capsules.
申请公布号
WO2011031617(A3)
申请公布日期
2011.07.28
申请号
WO2010US47652
申请日期
2010.09.02
申请人
FMC CORPORATION;GASEROD, OLAV;LARSEN, CHRISTIAN, KLEIN;ANDERSEN, PEDER, OSCAR
发明人
GASEROD, OLAV;LARSEN, CHRISTIAN, KLEIN;ANDERSEN, PEDER, OSCAR