发明名称 |
TREATMENT OF NUCLEAR RESPIRATORY FACTOR 1 (NRF1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO NRF1 |
摘要 |
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Nuclear Respiratory Factor 1 (NRF1), in particular, by targeting natural antisense polynucleotides of Nuclear Respiratory Factor 1 (NRF1). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of NRF1. |
申请公布号 |
CA2785173(A1) |
申请公布日期 |
2011.07.28 |
申请号 |
CA20102785173 |
申请日期 |
2010.12.29 |
申请人 |
CURNA, INC. |
发明人 |
COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA |
分类号 |
C12N15/113;A61K31/7088;A61K48/00;A61P25/00 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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