发明名称 |
Formation of Nanostructured Particles of Poorly Water Soluble Drugs and Recovery by Mechanical Techniques |
摘要 |
The present invention provides a composition and method of forming an amorphous drug-loaded particle by forming one or more amorphous drug-loaded nanoparticles comprising one or more active agents stabilized by one or more polymers, desolvating the one or more amorphous drug-loaded nanoparticles to form one or more flocculated amorphous drug-loaded nanoparticles, filtering the one or more flocculated amorphous drug-loaded nanoparticles and drying the one or more flocculated amorphous drug-loaded nanoparticles to form amorphous drug-loaded particles. |
申请公布号 |
US2011182946(A1) |
申请公布日期 |
2011.07.28 |
申请号 |
US20090933405 |
申请日期 |
2009.03.17 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
JOHNSTON KEITH P.;WILLIAMS, III ROBERT O.;MATTEUCCI MICHAL E. |
分类号 |
A61K9/14;A61K31/192;A61K31/496;A61P29/00;A61P31/00;B82Y5/00 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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