发明名称 Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity
摘要 The present invention is a compound having the general formula (I), (II), or (III) or a pharmacologically acceptable salt, solvate, or hydrate thereof, and a pharmaceutical composition containing such a compound, or its pharmacologically acceptable ester, or other pharmacologically acceptable derivative thereof as an active ingredient. The compound has an excellent ACAT 2-inhibiting activity by a mechanism different from that of a statin drug and is useful as a therapeutic or prophylactic agent for obesity, adiposis, hyperlipidemia, hypercholesterolemia, disorder of lipid metabolism, and arteriosclerosis, as well as obesity-derived hyperlipidemia, hypercholesterolemia, disorder of lipid metabolism, arteriosclerosis, and hypertension.
申请公布号 US2011184173(A1) 申请公布日期 2011.07.28
申请号 US20080810545 申请日期 2008.12.17
申请人 THE KITASATO INSTITUTE 发明人 TOMODA HIROSHI;NAGAMITSU TOHRU;OMURA SATOSHI
分类号 C07D401/14 主分类号 C07D401/14
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