发明名称 |
DEVICE AND METHOD FOR NON-INVASIVE MEASUREMENT OF THE INDIVIDUAL METABOLIC RATE OF A SUBSTANTIALLY SPHERICAL METABOLIZING PARTICLE |
摘要 |
The present invention relates to methods and devices for non-invasive and non-disturbing measurements of metabolizing rates of substantially spherical metabolizing particles, such as an embryo, and to a method and device for controlling oxygen partial pressure at the level of the embryo. Furthermore, the invention relates to a method for regulating supply of metabolites to a substantially spherical metabolizing particle, as well as a method for selecting substantially spherical metabolizing particles of a predetermined quality. The invention is carried out in a device capable of establishing a diffusion gradient of metabolites between the substantially spherical metabolizing particle inside a compartment in the device and the environment outside the compartment. The metabolizing rate is determined based on information of the metabolite diffusion gradient.
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申请公布号 |
US2011183367(A1) |
申请公布日期 |
2011.07.28 |
申请号 |
US20100948301 |
申请日期 |
2010.11.17 |
申请人 |
OTTOSEN LARS DITLEV MORCK;RAMSING NIELS B;DAMGAARD LARS R;GUNDERSEN JENS K |
发明人 |
OTTOSEN LARS DITLEV MORCK;RAMSING NIELS B.;DAMGAARD LARS R.;GUNDERSEN JENS K. |
分类号 |
C12Q1/02;A61B5/00;A61B5/083;C12M1/34;C12N5/06;C12N5/12;G01N33/497;G01N33/50 |
主分类号 |
C12Q1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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