发明名称 |
P-CADHERIN ANTIBODIES |
摘要 |
The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to P-cadherin, and that function to inhibit P-cadherin. The invention also relates to heavy and light chain immunoglobulins derived from human P-cadherin antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human P-cadherin antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention.
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申请公布号 |
US2011182884(A1) |
申请公布日期 |
2011.07.28 |
申请号 |
US201113079726 |
申请日期 |
2011.04.04 |
申请人 |
AGOURON PHARMACEUTICALS, INC. |
发明人 |
BAUER CHRISTOPHER TODD;BOURNER MAUREEN JERI;BOYLE MELANIE;CASPERSON GERALD FRIES;GRIGGS DAVID WILLIAM;HEAD RICHARD DAVID;JOY WILLIAM DEAN;MAZZARELLA RICHARD ALLEN;MINTER RALPH RAYMOND;MOFFAT MARK ALLEN;THIELE BARRETT RICHARD;VANARSDALE TODD LEE |
分类号 |
A61K39/395;A61P35/00;A61P35/02;C07K16/18 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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