发明名称 SYNTHESIS OF 6,7-DIHYDRO-1H-INDENO[5, 4-B] FURAN-8(2H)-ONE AS INTERMEDIATE IN THE PREPARATION OF REMELTEON
摘要 The present invention describes the preparation of 6,7-dihydro-1H-indeno[5,4-b]furan-8(2H)-one, a key intermediate in preparation of ramelteon. The present invention also describes further preceding intermediate compounds useful for the synthesis of 6,7-dihydro-1H-indeno[5,4-b]furan-8(2H)-one.
申请公布号 US2011184058(A1) 申请公布日期 2011.07.28
申请号 US200913054025 申请日期 2009.07.13
申请人 LEK PHARMACEUTICALS D.D. 发明人 CLUZEAU JEROME
分类号 A61K31/343;A61P25/00;C07D307/78 主分类号 A61K31/343
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