发明名称 |
MEGASTIGMANE DERIVATIVES ISOLATED FROM ILEX PARAGUARIENSIS, PREPARATION METHOD THEREOF AND ANTI-WRINKLE COMPOSITION CONTAINING THE SAME AS AN ACTIVE INGREDIENT |
摘要 |
PURPOSE: A novel megastigmane derivative or pharmaceutically acceptable salt thereof is provided to prevent or treat wrinkling. CONSTITUTION: A megastigmane derivative or pharmaceutically acceptable salt thereof is denoted by chemical formula 1 or 2. A method for preparing the megastigmane derivative comprises: a step of adding water, organic solvent, or mixture solvent thereof to Ilex paraguariensis to prepare Ilex paraguariensis extract; a step of fractioning the Ilex paraguariensis extract with n-hexane and ethyl acetate to prepare an Ilex paraguariensis fraction; and a step of performing column chromatography.
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申请公布号 |
KR20110085151(A) |
申请公布日期 |
2011.07.27 |
申请号 |
KR20100004768 |
申请日期 |
2010.01.19 |
申请人 |
HANKOOK PHARM. CO., INC. |
发明人 |
YOO, ICK DONG;XU GUANGHUA;YOO, JAE KUK;KIM, JIN PYO |
分类号 |
A61K31/7028;A61K8/97;A61Q19/00 |
主分类号 |
A61K31/7028 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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