发明名称 |
A method for producing influenza hemagglutinin multivalent vaccines |
摘要 |
Recombinant influenza haemagglutinin (HA0) expressed in a baculovirus expression system in cultured insect cells is new. Also new is a vector for prodn. of recombinant HA0 comprises, in 5' to 3' sequence, a polyhedrin baculovirus promoter, ATG start codon, signal peptide (SP) sequence, sequence for mature HA0, stop codon and polyhedrin RNA polyadenylation signal. |
申请公布号 |
EP1605052(B1) |
申请公布日期 |
2011.07.27 |
申请号 |
EP20050076536 |
申请日期 |
1995.05.26 |
申请人 |
PROTEIN SCIENCES CORPORATION |
发明人 |
SMITH, GALE EUGENE;VOLVOVITZ, FRANKLIN;WILKINSON, BETHANIE E.;VOZNESENSKY, ANDREI I.;HACKETT, CRAIG STANWAY |
分类号 |
C12N15/09;C12N15/86;A61K39/00;A61K39/145;A61P31/16;A61P37/04;C07K;C07K14/085;C07K14/11;C07K14/155;C07K14/82;C07K19/00;C12N;C12N5/10;C12N9/24;C12N15/44;C12N15/62;C12N15/866;C12P21/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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