| 发明名称 |
USE OF PYRIDINE-2,4-DICARBOXYLIC ACID DIAMIDES AND OF PYRIMIDINE-4,6-DICARBOXYLIC ACID DIAMIDES FOR SELECTIVE COLLAGENASE INHIBITION |
| 摘要 |
The invention concerns pyridine-2,4-dicarboxylic acid diamides and pyrimidine-4,6-dicarboxylic acid diamides of formula (I) for selective collagenase (MMP 13) inhibition. Said pyridine-2,4-dicarboxylic acid diamides and pyrimidine-4,6-dicarboxylic acid diamides can therefore be used for treating degenerative joint diseases.
|
| 申请公布号 |
CA2469625(C) |
申请公布日期 |
2011.07.26 |
| 申请号 |
CA20022469625 |
申请日期 |
2002.11.25 |
| 申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
WEITHMANN, KLAUS-ULRICH;HABERMANN, JOERG;KOGLER, HERBERT;KIRSCH, REINHARD;WEHNER, VOLKMAR |
| 分类号 |
C07D239/28;A61K31/44;A61K31/4409;A61K31/443;A61K31/4433;A61K31/505;A61K31/506;A61P1/02;A61P17/02;A61P19/00;A61P19/02;A61P19/04;A61P19/08;A61P29/00;A61P35/00;A61P43/00;C07D213/81;C07D405/12;C07D405/14 |
主分类号 |
C07D239/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
