发明名称 |
Pharmaceutical composition comprising a bi-cyclic compound and method for stabilizing the bi-cyclic compound |
摘要 |
Disclosed is a method for stabilizing a pharmaceutically active bi-cyclic compound of formula (i): comprising the step of: admixing the same with a polyol and/or a fatty acid ester other than glyceride and a composition obtained by the method. In addition a soft gelatin capsule formulation of the compound of formula (I) obtained by incorporating the compound in a soft gelatin capsule shell comprising gelatin and a polyol plasticizer.
|
申请公布号 |
US7985770(B2) |
申请公布日期 |
2011.07.26 |
申请号 |
US20070656513 |
申请日期 |
2007.01.23 |
申请人 |
SUCAMPO AG;R-TECH UENO, LTD. |
发明人 |
HIRATA RYU;HARADA YASUHIRO;UENO RYUJI |
分类号 |
A61K31/4741;A61K9/48;A61K31/35;A61K31/353;A61K31/382 |
主分类号 |
A61K31/4741 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|