发明名称 |
Heterodimeric receptor libraries using phagemids |
摘要 |
Filamentous phage comprising a matrix of cpVIII proteins encapsulating a genome encoding first and second polypeptides of an antogenously assembling receptor, such as an antibody, and a receptor comprised of the first and second polypeptides surface-integrated into the matrix via a filamentous phage coat protein membrane anchor domain fused to at least one of the polypeptides.
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申请公布号 |
US7985841(B2) |
申请公布日期 |
2011.07.26 |
申请号 |
US20050315970 |
申请日期 |
2005.12.22 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
KANG ANGRAY;BARBAS CARLOS F.;LERNER RICHARD A. |
分类号 |
C12N15/09;C12P21/08;C07K14/00;C07K14/705;C07K16/00;C07K16/40;C07K19/00;C12N7/00;C12N7/01;C12N15/10;C12N15/62;C12N15/70;C40B40/02;C40B50/06;G01N33/53;G01N33/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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