发明名称 ANTIBODIES AGAINST INSULIN-LIKE GROWTH FACTOR I RECEPTOR AND USES THEREOF
摘要 An antibody binding to IGF-IR, being of human IgG1 or IgG3 type and being glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is at least 99 %, and in addition the amount of NGNA is 1 % or less and/ or the amount of N-terminal alpha-1,3-galactose is 1 % or less has improved properties in antitumor therapy.
申请公布号 UA95284(C2) 申请公布日期 2011.07.25
申请号 UA20080012606 申请日期 2007.04.10
申请人 F. HOFFMANN-LA ROCHE AG 发明人 HANSEN SILKE;KUENKELE KLAUS-PETER;REUSCH DIETMAR;SCHUMACHER, RALF
分类号 C07K16/28 主分类号 C07K16/28
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