发明名称 |
Group of amino substituted benzoyl derivatives and their preparation and their use |
摘要 |
A group of amino substituted benzoyl derivatives, their preparation and their use. The screening and research on an antiviral drug with hA3G/Vif as a target point proves that the 3-amino benzoyl derivatives not only have the combined activity for the hA3G/Vif, but also have a function of inhibiting replication of viruses. The present invention provides the possible breakthrough progress for the problem of HIV drug resistance, thereby providing a novel clinical antiviral drug which has higher efficiency.
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申请公布号 |
US2011178108(A1) |
申请公布日期 |
2011.07.21 |
申请号 |
US20090998210 |
申请日期 |
2009.09.28 |
申请人 |
INSTITUTE OF MEDICINAL BIOTECHNOLOGY ACADEMY OF MEDICAL SCIENCE |
发明人 |
JIANG JIAN-DONG;YU LIYAN;CEN SHAN;LI ZHOURONG;LI YANPING;XU JLAN |
分类号 |
A61K31/505;A61K31/167;A61K31/21;A61K31/245;A61K31/27;A61K31/341;A61P31/12;C07C229/64;C07C231/02;C07C237/44;C07C271/28;C07C327/28;C07D239/47;C07D307/66 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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地址 |
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