MATERIALS AND METHODS RELATED TO SODIUM/POTASSIUM ADENOSINE TRIPHOSPHASE AND CHOLESTEROL
摘要
This invention is based in part on the elucidation of new structural conformations and functions of the sodium/potassium adenosine triphosphate synthase (Na/K ATPase), and especially elucidation of new binding sites and interactions. The present invention provides practical applications of several surprising structural and functional relationships between Na/K ATPase and compounds which interact with Na/K ATPase. Disclosure of these structures and relationships provides insight and practical solutions to chemically affecting not only the Na/K ATPase interactions, but also regulators known to be upstream and downstream.
申请公布号
WO2011088208(A1)
申请公布日期
2011.07.21
申请号
WO2011US21127
申请日期
2011.01.13
申请人
THE UNIVERSITY OF TOLEDO;XIE, ZIJIAN;CHEN, YILIANG;WANG, HAOJIE