发明名称 |
INDIVIDUAL 5-FLUOROURACILE DOSE OPTIMIZATION IN FOLFIRI TREATMENT |
摘要 |
The present invention belongs to the field of improved personalized medicine. More precisely, the present invention relates to a method for progressively optimizing the 5-FU dose administered by continuous infusion in patients treated by a FOLFIRI regimen or a similar regimen, based on the 5-FU plasmatic concentration measured during the previous 5-FU continuous infusion and on a herein described decision algorithm. The present invention also relates to a method for treating a cancer patient in which the 5-FU dose administered in continuous infusion in each FOLFIRI or similar treatment cycle is optimized using the decision algorithm according to the invention. |
申请公布号 |
US2011177092(A1) |
申请公布日期 |
2011.07.21 |
申请号 |
US200813121103 |
申请日期 |
2008.09.26 |
申请人 |
CENTRE REGIONAL DE LUTTE CONTRE LE CANCER D'ANGERS |
发明人 |
GAMELIN ERICK;BOISDRON-CELLE MICHELE;MOREL ALAIN |
分类号 |
A61K39/395;A61P35/00;C12Q1/02 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|