发明名称 |
GENE EXPRESSION PROFILE THAT PREDICTS OVARIAN CANCER SUBJECT RESPONSE TO CHEMOTHERAPY |
摘要 |
A gene profiling signature is disclosed herein. The gene signature can predict whether a subject with ovarian cancer will be chemorefractory, chemoresistant or chemosensitive. Thus, methods are disclosed for determining whether a subject with ovarian cancer is sensitive to treatment with a chemotherapeutic agent. Methods are also provided for increasing sensitivity to the chemotherapeutic agent if the presence of differential expression indicates that the ovarian cancer has a decreased sensitivity to chemotherapeutic agent.
|
申请公布号 |
US2011178154(A1) |
申请公布日期 |
2011.07.21 |
申请号 |
US20080526025 |
申请日期 |
2008.02.06 |
申请人 |
BIRRER MICHAEL J;OZBUN LAURENT L;BONOME TOMAS A;MOK SAMUEL |
发明人 |
BIRRER MICHAEL J.;OZBUN LAURENT L.;BONOME TOMAS A.;MOK SAMUEL |
分类号 |
A61K31/713;A61P35/00;C12Q1/68;C40B30/00;C40B30/04;C40B40/00;G01N33/68 |
主分类号 |
A61K31/713 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|