发明名称 |
MODIFIED VASOACTIVE INTESTINAL PEPTIDES |
摘要 |
The present invention provides modified Vasoactive Intestinal Peptides (VIPs), encoding polynucleotides and vectors, as well as pharmaceutical compositions comprising the same. The invention further provides methods of making and using the modified VIP agents. In accordance with the invention the VIP exhibits an extended circulatory half-life, receptor-binding or biological potency, and/or altered receptor binding profile with respect to unmodified VIP.
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申请公布号 |
US2011178017(A1) |
申请公布日期 |
2011.07.21 |
申请号 |
US20100857103 |
申请日期 |
2010.08.16 |
申请人 |
PHASEBIO PHARMACEUTICALS, INC. |
发明人 |
SADEGHI HOMAYOUN;DAGHER SUZANNE;TURNER ANDREW |
分类号 |
A61K38/22;A61P3/10;A61P9/10;A61P9/12 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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