| 摘要 |
FIELD: medicine. ^ SUBSTANCE: group of inventions refers to medicine and medical equipment, namely to methods for conducting interstitial laser hyperthermia and photodynamic therapy of malignant neoplasms located under skin or in soft tissues, and apparatuses to implement said method. The apparatus comprises a laser emitter, an attached light guide, a cooling assembly for contact cooling of a tissue surface, a coolant supply means and a temperature recording device. The latter comprises an infrared chamber connected to a data displaying and processing unit connected with the laser emitter and the coolant supply means. The cooling assembly represents a seal unit with two sapphire windows. They are separated with a hollow for coolant supply. The light guide is fastened on a seal box by a bushing via a threaded connection. The data displaying and processing unit calculates a temperature value at the preset depth directly under the cooling assembly and regulates the power of the laser emitter and the rate of coolant supply by the means. The given apparatus is used in the laser hyperthermia and PDT method. The temperature is recorded on the tissue surface along the perimetre of the cooling assembly and/or at the certain distance therefrom. The input and output coolant temperature is recorded. The measured temperature values are used to derive the temperature directly under the cooling assembly at the preset depth. The temperature under the cooling assembly at the set depth is changed to the required value by regulating the laser emission power and/or coolant supply rate. ^ EFFECT: use of the group of inventions will allow higher effectiveness of laser hyperthermia and PDT of the malignant neoplasms located under skin or in soft tissues due to nonuniform tissue heating, enabled emission regulation of a temperature gradient position in the depth of the tissue, more effective radiation delivery, minimised skin injuries. ^ 8 cl, 4 dwg |
