发明名称 |
ORAL VACCINES FOR PRODUCING MUCOSAL IMMUNITY |
摘要 |
<p>Embodiments of this invention include lipid-based immunogenic compositions (adjuvants or carriers) useful for oral or gastrointestinal administration for improving mucosal immune responses in animals vaccinated for a variety of bacterial infections. In certain embodiments, lipid compositions of this invention include a mixture of fatty acids having different chain lengths, thereby providing desired physico-chemical properties. When a bacterial antigen is mixed with a lipid-based adjuvant or carrier, the resulting composition elicits improved mucosal immune responses and thereby decreases infections and sequellae of disease caused by Chlamydia or Helicobacter.</p> |
申请公布号 |
EP2344152(A2) |
申请公布日期 |
2011.07.20 |
申请号 |
EP20090818862 |
申请日期 |
2009.10.07 |
申请人 |
IMMUNE SOLUTIONS LIMITED |
发明人 |
ALDWELL, FRANK, E.;BEAGLEY, KENNETH, W. |
分类号 |
A61K31/20;A61K39/02;A61K39/118;A61P31/04;A61P37/00 |
主分类号 |
A61K31/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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