| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to methods for chemoselective pegylation of a cysteine residue, having an unoxidised sulfhydryl side chain and a free -amino group in peptides. ^ EFFECT: disclosed are similar methods for chemoselective pegylation of homo-cysteine, selenocysteine, penicillamine and N-methylcysteine residues. ^ 13 cl, 19 ex |
